Season 2

01 A Son in the Oven Episode 113th October 2025 Watson and the fellows spring back into action when Mary’s mother accidentally poisons herself while suffering from a rare form of dementia that is progressing with impossible speed. Meanwhile, Sherlock Holmes resurfaces after being presumed dead. 02 Back from the Dead Episode 220th October 2025 A microbiology researcher returns from an expedition to Siberia, leading to a possible outbreak of a revived pathogen. Watson reconnects with Sherlock Holmes. 03 Expletive Deleted Episode 327th October 2025 Watson and the team work alongside Laila to help a patient named Maxine, a 30-year-old who looks 10 years old. 04 Happy When It Rains Episode 43rd November 2025 Watson and the team jump into action when four new patients are brought to UHOP with wounds that appear to be infected with a flesh-eating bacterium following a tornado. Meanwhile, Shinwell searches for meaning as a nursing student and Adam’s wedding to Lauren risks being halted. 05 Lucky Episode 510th November 2025 While visiting another hospital, Watson becomes convinced that a coma patient is suffering from locked-in syndrome and has been mistaken for a coma patient for over a decade. After the patient is transferred to UHOP for treatment, he shocks the team with chilling messages. Meanwhile, Sherlock is back in town and is staying with Watson. 06 Buying Time Episode 617th November 2025 Watson and the fellows race against time to save the life of Xavier, a 21-year-old athlete with a fast-growing, seemingly incurable cancer. Meanwhile, Mycroft Holmes lets Watson know his team’s work at UHOP may no longer have funding available. 07 Giant Steps Episode 724th November 2025 Watson's father, Hamish, visits UHOP to introduce Watson and the fellows to his protégé, Annabelle, a saxophone prodigy with musically induced blackouts. As Annabelle's condition worsens, Watson must confront his long-standing tensions with his father in order to save her. 08 Livvy Sees the Doctor Episode 81st December 2025 UHOP veers into terror when Watson and the fellows are taken hostage by a man with a bomb strapped to his chest who is desperate to find a cure for his 9-year-old daughter’s illness. 09 Shannon Says Bex Loves Micah Episode 98th December 2025 Watson and the fellows help Laila’s son Micah – who was injured in a car accident while pursuing his crush, Bex, with the help of his AI chatbot. 10 Never Been CRISPR'd Episode 1015th December 2025 Watson’s biohacker friend Hobie returns when he rushes his new girlfriend to the Holmes Clinic after they partake in a gene-editing experiment that goes wrong. Meanwhile, Watson becomes suspicious of Sherlock. 11 The Tunnel Under the Elms Episode 111st March 2026 Watson and the fellows race against the clock to save a man and his pregnant wife from a terrifying sinkhole. Meanwhile, Ingrid’s future with her therapy group becomes unclear. 12 A Family Meal Episode 128th March 2026 When a patient arrives at the Holmes Clinic plagued by a mysterious neurological disorder, Watson and the fellows discover they were forced to eat their parents amid a childhood survival incident. Meanwhile, Adam is struggling with how his future will change as a father. 13 For a Limited Time Only Episode 1315th March 2026 Watson and the fellows fight to revive a 30-year-old woman, Audrey, after her heart inexplicably stops repeatedly until they discover she has a rare phenomenon called Lazarus syndrome. As these revivals continue, she uses the short window of time available to right her greatest wrong. 14 Wrongful Life Episode 1422nd March 2026 Watson is sued for Wrongful Life by a long-term patient suffering from VACTERL association, after undergoing multiple painful surgeries. 15 A Third Act Surprise Episode 1529th March 2026 Watson and the fellows race to save the life of a young woman who needs a lifesaving kidney donation. Meanwhile, Sherlock returns to help crack unsolved cases in Pittsburgh. 16 Respect the Process. Respect the Quirks Episode 165th April 2026 Watson investigates a case involving a mentally unstable mother, with the woman's delusions serving as a mirror to his own newly discovered hallucinations. 17 Unsolved Mysteries Episode 1712th April 2026 In the wake of the car accident, Watson and Laila lie injured and awaiting rescue as the team races to find them before it’s too late. Meanwhile, in a state between life and death, Watson’s mind plays out a modern-day investigation of a case that has long haunted him. 18 Sic Semper Tyrannis Episode 1819th April 2026 Following his brain tumor diagnosis, Watson goes on medical leave to seek treatment, leaving Mary in charge of The Holmes Clinic as a notorious South American dictator demands Watson see to his mysterious autoimmune condition personally. Meanwhile, Ingrid grows more concerned about Beck’s obsession with Sasha. 19 Rule of Three Episode 1926th April 2026 As Adam's wife goes in for a C-section to deliver triplets, chaos ensues when their OB-GYN passes out in the operating room. Meanwhile, a severe storm detours Watson and Mary's trip to find a renowned doctor to remove Watson's brain tumor. 20 The Cobalt Fissure Episode 203rd May 2026 A seemingly random murder outside of UHOP sets the stage for the arrival of someone from Watson and Sherlock Holmes' past.