Season 22

01 Luke Wilson, Julie Chen, Lee Brice Episode 12nd September 2014 02 Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers Episode 23rd September 2014 03 Steve Buscemi, Indy Car Season Champ, Alt-J Episode 34th September 2014 04 Tina Fey, Moody McCarthy, Kevin Drew Episode 45th September 2014 05 Bill Maher, Henrik Lundqvist, Spoon Episode 58th September 2014 06 Michael Strahan, Richard Branson, Interpol Episode 69th September 2014 07 Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson Episode 710th September 2014 08 Jason Bateman, Billy Eichner, Ryan Adams Episode 811th September 2014 09 Mindy Kaling, Jake Johannsen, Maddie & Tae Episode 912th September 2014 10 Mark Harmon, "Jungle" Jack Hanna Episode 1022nd September 2014 11 Denzel Washington, Lenny Kravitz Episode 1123rd September 2014 12 Kelly Ripa, Jim Gaffigan, Paloma Faith Episode 1224th September 2014 13 Jerry Seinfeld, Michael Jackson ONE Episode 1325th September 2014 14 Ted Danson, Andrew Norelli Episode 1426th September 2014 15 Neil Patrick Harris, Jamie Oliver, Aretha Franklin Episode 1529th September 2014 16 John Oliver, Maggie Q, Bleachers Episode 1630th September 2014 17 Bill O'Reilly, Cristin Milioti Episode 171st October 2014 18 Johnny Galecki, Andre Benjamin, Delta Spirit Episode 182nd October 2014 19 Mariska Hargitay, Simon Amstell, Kandace Springs Episode 193rd October 2014 20 Aziz Ansari, Tom Dreesen Episode 206th October 2014 21 Robert Downey Jr., Sarah Paulson, Lizzo Episode 217th October 2014 22 Anderson Cooper, Gina Rodriguez, Hatsune Miku Episode 228th October 2014 23 Robert Duvall, Elle Fanning, Rival Sons Episode 239th October 2014 24 Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley Episode 2410th October 2014 TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs. 25 Russell Brand, Dave Grohl, Foo Fighters Episode 2513th October 2014 26 Michael Keaton, Foo Fighters Episode 2614th October 2014 27 Bill Murray, Foo Fighters Episode 2715th October 2014 28 Tom Selleck, Jenny Slate, Foo Fighters Episode 2816th October 2014 29 Jessica Chastain, Lenny Marcus, Foo Fighters Episode 2917th October 2014 30 Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis Episode 3027th October 2014 31 Taylor Swift, Tom Mison Episode 3128th October 2014 32 Jim Carrey, David Tennant Episode 3229th October 2014 33 Brian Williams, Perfume Genius Episode 3330th October 2014 34 Keith Olbermann, Brian Regan, Run the Jewels Episode 3431st October 2014 35 Martin Short, Father John Misty Episode 353rd November 2014 36 Jennifer Lopez, Rob Riggle, Kimbra Episode 365th November 2014 37 Whoopi Goldberg, Jimmy Page, Mapei Episode 376th November 2014 38 Amy Schumer, Jeff Caldwell Episode 387th November 2014 39 Katie Holmes, Alex Zanardi Episode 3910th November 2014 40 Steve Carell, Martha Stewart, OK Go Episode 4011th November 2014 41 Jennifer Lawrence, Boris Johnson Episode 4112th November 2014 42 Jon Stewart, Shawn Mendes Episode 4213th November 2014 43 Kristin Chenoweth; Chris Young Episode 4314th November 2014 Actress Kristin Chenoweth; Chris Young performs. 44 Jason Sudeikis, Allison Janney, Damien Rice Episode 4417th November 2014 45 Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger Episode 4518th November 2014 46 Regis Philbin, Hundred Waters Episode 4619th November 2014 47 Edward Norton, Jessye Norman Episode 4720th November 2014 48 Norman Lear, TV on the Radio Episode 4821st November 2014 49 Seth Rogen, Amy Sedaris Episode 4924th November 2014 50 Emily Blunt, Adam Resnick, Wu-Tang Clan Episode 5025th November 2014 51 Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz Episode 5126th November 2014 52 Joaquin Phoenix, Cristela Alonzo, Al Green Episode 528th December 2014 53 Ben Stiller, Olivia Munn, LaLa Brooks Episode 539th December 2014 54 Meryl Streep, Rebel Wilson, J. Cole Episode 5410th December 2014 55 Chris Rock, Sting Episode 5511th December 2014 56 Jamie Foxx, Robert Klein, Dan Penn Episode 5612th December 2014 57 Emma Stone Top, Marcus Mariota, Bob Seger Episode 5715th December 2014 58 New Holiday Toys, Anna Kendrick, Charli XCX Episode 5816th December 2014 59 Tom Brokaw, Will Nelson & Billy Joe Shaver Episode 5917th December 2014 60 Rosie O’Donnel,l Jeff Altman Episode 6018th December 2014 61 Jay Thomas, Josh Brolin, Darlene Love Episode 6119th December 2014 The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home). 62 Kathy Griffin, David Oyelowo, Lera Lynn Episode 625th January 2015 63 Ethan Hawke, Allison Williams, Parquet Courts Episode 636th January 2015 64 Julianne Moore, Catfish & the Bottlemen Episode 647th January 2015 65 Donald Trump, Chelsea Peretti, Foxygen Episode 658th January 2015 66 Michael Somerville, Nicole Atkins Episode 669th January 2015 67 Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones Episode 6712th January 2015 68 Anderson Cooper, Shovels & Rope Episode 6813th January 2015 69 Amanda Peet, Ryn Weaver Episode 6914th January 2015 70 Larry David, Dan Patrick, Sleater-Kinney Episode 7015th January 2015 71 Urban Meyer, Johnny Beehner, Ella Henderson Episode 7116th January 2015 72 Louis CK, Nicolle Wallace, the Lone Bellow Episode 7226th January 2015 73 Andrew Luck, Oscar Isaac, Drenge Episode 7327th January 2015 74 Viola Davis, Ben Schwartz, Marty Stuart Episode 7428th January 2015 75 John Oliver, Mayim Bialik, Death Cab for Cutie Episode 7529th January 2015 76 Aziz Ansari, Brian Kiley, Ben Howard Episode 7630th January 2015 77 Jack Hanna, Sharon Jones and the Dap-Kings Episode 772nd February 2015 78 Dr. Phil McGraw, Robin Tunney, Diana Krall Episode 783rd February 2015 79 Ryan Reynolds, Dierks Bentley Episode 794th February 2015 80 Martin Short, Bettye Lavette Episode 805th February 2015 81 Sienna Miller, Andy Kindler, Bob Mould Episode 816th February 2015 82 Steve Carell, Dr. Cornel West Episode 829th February 2015 83 Courtney Love, Chris Elliott, Rhiannon Giddens Episode 8310th February 2015 84 Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear Episode 8411th February 2015 85 Tom Hanks, Sturgill Simpson Episode 8512th February 2015 86 Bill Hader, Pat McGann, Shakey Graves Episode 8613th February 2015 87 Matthew Perry, Adam Scott, Kishi Bashi Episode 8716th February 2015 88 Dakota Johnson, David Tochinskiy, Twin Shadow Episode 8817th February 2015 89 Will Smith, Grizfolk Episode 8918th February 2015 90 Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko Episode 9019th February 2015 91 Kid Scientists, Sean Hayes, Judah & the Lion Episode 9120th February 2015 92 Helen Mirren, the 2015 Daytona 500 winner, Steve Earle Episode 9223rd February 2015 93 Matthew Broderick, Ellie Kemper, JD McPherson Episode 9324th February 2015 94 Julianna Margulies, Eric Ripert, Glass Animals Episode 9425th February 2015 95 Kevin Spacey, Lily James, Alabama Shakes Episode 959th March 2015 96 Patricia Arquette, Will Butler Episode 9610th March 2015 97 Kelsey Grammer, Stevie Wonder Episode 9711th March 2015 98 Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew Episode 9812th March 2015 99 Kevin Bacon, Jimmie Walker, Airborne Toxic Event Episode 9913th March 2015 100 Shailene Woodley, Dr. Cornel West, Matthew E. White Episode 10016th March 2015 101 Will Ferrell, Glen Hansard Episode 10117th March 2015 102 Norm MacDonald, Theo James Episode 10218th March 2015 103 Ben Stiller, Tove Lo Episode 10323rd March 2015 104 Bill O'Reilly, Aubrey Plaza Episode 10424th March 2015 105 James Franco, Jake Johannsen, Action Bronson Episode 10525th March 2015 106 Neil Patrick Harris, Charlie Cox, the Suffers Episode 10630th March 2015 107 David Duchovny, Josh Gad, Houndmouth Episode 10731st March 2015 108 Sen. Al Franken, Billy Eichner, David Sanborn Episode 1081st April 2015 109 Kelly Ripa, Aasif Mandvi, Fat White Family Episode 1092nd April 2015 110 Mike Myers, Nick Griffin, Banks Episode 1103rd April 2015 111 Sarah Jessica Parker, Julie Chen, Asleep at the Wheel Episode 11113th April 2015 112 Billy Crystal, Chris Russo, Chris Stapleton Episode 11214th April 2015 113 Michael J. Fox, Iron & Wine, Ben Bridwell Episode 11315th April 2015 114 Kevin James, Tom Dreesen, Tracy Chapman Episode 11416th April 2015 115 Alec Baldwin, John Mayer Episode 11517th April 2015 116 John Travolta, Amy Schumer, the Waterboys Episode 11620th April 2015 117 Piedmont Bird Callers, Paul Rudd Episode 11721st April 2015 118 Bruce Willis, Dawes Episode 11822nd April 2015 119 Robert Downey Jr., Chris Russo, Elvis Costello Episode 11923rd April 2015 120 Jerry Seinfeld, Jason Isbell & Amanda Shires Episode 12024th April 2015 121 Scarlett Johansson, John Mellencamp, Todd Rundgren Episode 12127th April 2015 122 Michael Keaton, Future Islands Episode 12228th April 2015 123 Jack Hanna, John Popper Episode 12329th April 2015 124 First Lady Michelle Obama Hootie and the Blowfish Episode 12430th April 2015 125 Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor Episode 1251st May 2015 126 President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile Episode 1264th May 2015 127 Reese Witherspoon, Nathan Lane, Mumford & Sons Episode 1275th May 2015 128 Martin Short, Norah Jones Episode 1286th May 2015 129 Tina Fey, First Aid Kit Episode 1297th May 2015 130 Ray Romano, Brian Regan, Dave Matthews Band Episode 1308th May 2015 131 Howard Stern, Don Rickles Episode 13111th May 2015 132 Bill Clinton, Adam Sandler Episode 13212th May 2015 133 Julia Roberts, Paul Shaffer, Ryan Adams Episode 13313th May 2015 134 Al Pacino, George Clooney, Tom Waits Episode 13414th May 2015 135 Oprah Winfrey, Norm Macdonald Episode 13515th May 2015 136 Tom Hanks, Eddie Vedder Episode 13618th May 2015 137 Bill Murray, Bob Dylan Episode 13719th May 2015 138 The Final Late Show with David Letterman Episode 13820th May 2015 6,028th broadcast 139 Episode 149 Episode 14920th May 2015 The final episode includes surprises, memorable highlights and the last Top Ten List.