Breath of Life

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Horizon
12th January 2000 1 hour Season 37 Episode 1

In this moving film Horizon follows the Loughran family in their fight to save the life of their daughter Sheila who suffers from cystic fibrosis. They lost their youngest daughter Ann to the disease in 1974 at the age of 15, and now as the health of their third daughter Sheila deteriorates, they must face the prospect of losing a second child. The current shortage of donor organs means that Sheila's only hope of survival is a rare and controversial operation that requires her two surviving siblings to undergo an arduous and potentially fatal operation. An X-ray of Shelia's lungs Cystic fibrosis (CF) is the most common genetic disease in this country and it is incurable. The lungs of people with cystic fibrosis become covered with a sticky mucus making them extremely susceptible to bacterial infection. Over time these infections badly scar the lungs, until eventually they stop functioning. The defective CF gene is harmless when only a single copy of the gene is inherited. However, both the Loughran parents carry the gene, giving any child they may have a 25% chance of being born with cystic fibrosis. In fact two of their four children were born with the condition. Horizon joins the family at a time when Sheila's health has deteriorated to such an extent that she requires oxygen 24 hours a day and has only months to live. Although on the waiting list for a donor lung, with 50% of patients dying while waiting to receive a transplant, Sheila's chances are not good. The family has become aware of a controversial new operation, pioneered in the UK by Professor Sir Magdi Yacoub at Harefield Hospital. The technique, known as Living Donor Lung Transplantation, would involve removing Sheila's diseased lungs and, in an extraordinary three-way operation, replacing them with a lobe from one of the lungs of each her two siblings. There have been six of these groundbreaking operations carried out in this country. However, only three patients have lived longer than a month. There is a clear moral dilemma - with such a low success rate, is it ethical to put the lives of two healthy people at risk? Even if the operation is initially successful it may only give Sheila five more years to live, by which time her new lungs are likely to fail again. Damian Loughran Sheila's brother and sister, Damian and Josephine, feel compelled to do anything they can to save their dying sister. They undergo stringent tests before being certain that they are compatible donors and fit for surgery. They will have to face the risk of haemorrhaging and infection, both of which could potentially be fatal. After the operation both donors will be left with a 20-25% permanent loss of lung function. Despite these dangers, Damian and Josephine remain determined to proceed. As all three of their children are wheeled in for the 12-hour operation, Mary and Harry Loughran's emotion is apparent. A day later, Sheila is breathing with her new lungs, but it is not long before complications arise. She is unable to absorb food and develops an abscess on her lung. Sheila is kept under sedation and so is unaware of these complications. Sadly, three weeks after the operation, Sheila loses her fight for life.

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The Lost City of Nasca still
Season 37 · Episode 2

The Lost City of Nasca

On a barren desert in South America lies one of the greatest archaeological puzzles in the world. Etched in the surface of the desert pampa sand are hundreds of straight lines, geometric shapes and pictures of animals and birds - and their patterns are only clearly visible from the air. They were built by a people called the Nasca - but why and how they created these wonders of the world has defied explanation. On the pampa, south of the Nasca Lines, archaeologists have now uncovered the lost city of the line-builders, Cahuachi. It was built nearly two thousand years ago and was mysteriously abandoned 500 years later. New discoveries at Cahuachi are at last beginning to give us insight into the Nasca people and to unravel the mystery of the Nasca Lines. Distorted heads The Lines were first spotted when commercial airlines began flying across the Peruvian desert in the 1920's. Passengers reported seeing 'primitive landing strips' on the ground below. No one knew who had built them or indeed why. Since their discovery, the Nasca Lines have inspired fantastic explanations. SpiderPerhaps most famously, the Austrian writer Erich von Danikken claimed that they were evidence that the earth had been visited by extra-terrestrials. The lines, he said, were runways for their spacecraft. Scientific study began in the 1940s with the arrival of a German mathematician and astronomer called Maria Reiche. She lived at Nazca until her death in 1998 and was known as the Lady of the Lines. Reiche believed that the lines were a sophisticated astronomical calendar. However, in 1965, astronomer Gerald Hawkins came to Nazca and used computers to check Reiche's theory. Hawkins could find no correlation between the lines and the stars. Giuseppe Orefici Italian archaeologist Giuseppe Orefici has been excavating the immense Cahuachi site for the last 17 years. Every year he brings a team of specialists to South America for three, intensive months of excavation. Horizon joined Orefici and his team in the hot, windy months of 1998 and this is a fascinating record of their extraordinary finds. Woven clothCahuachi is emerging as a treasure trove of the Nasca culture. As Orefici and his team excavate, discoveries of paintings on preserved pottery, and the ancient technique of weaving that the Nasca people developed, have given an insight into how the lines may have been made, and what they might have been used for, more than 1500 years ago. MummyMost exciting is the discovery of human remains. Stunningly preserved in the dry soil of the Peruvian desert are the mummified bodies of the Nasca themselves. Orefici's colleagues Brian Harrison and Andrea Drusini carry out modern autopsies on these remarkable finds, and reveal the strange world and rituals of the Nasca people. CahuachiOriginally believed to have been a military stronghold, Cahuachi is now reckoned to be a place of ritual and ceremony, and Orefici's stunning new evidence confirms this idea. Cahuachi is now revealed to have been abandoned after a series of natural disasters destroyed the city. But before they left it, the Nasca people covered the city in the arid pampa sand where, until recently, it has remained a barely visible mound in the desert.

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